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<br /> EPA's Headquarters Professionals'Union Opposes Fluoridation 10/11/11 11:45 PM
<br /> expressed in milligrams of chemical per kilogram of body weight,that a person can receive over the long term with reasonable
<br /> assurance of safety from adverse effects.Application of this methodology to the Varner et al.(4)data leads to a Reference Dose for
<br /> fluoride of 0.000007 mg/kg-day. Persons who drink about one quart of fluoridated water from the public drinking water supply of the
<br /> District of Columbia while at work receive about 0.01 mg/kg-day from that source alone. This amount of fluoride is more than 100
<br /> times the Reference Dose. On the basis of these results the union filed a grievance, asking that EPA provide un-fluoridated drinking
<br /> water to its employees.
<br /> The implication for the general public of these calculations is clear. Recent, peer-reviewed toxicity data,when applied to EPA's
<br /> standard method for controlling risks from toxic chemicals, require an immediate halt to the use of the nation's drinking water
<br /> reservoirs as disposal sites for the toxic waste of the phosphate fertilizer industry(24).
<br /> *Read an interview with Dr Hirzy concerning the N-P's Fluoride Cancer s tndy
<br /> *Read Dr. Hirzy's June 2000 Testimony to the US Senate
<br /> This document was prepared on behalf of the National Treasury Employees Union Chapter 280 by Chapter Senior Vice-President J.
<br /> William Hirzy, Ph.D. For more information please call Dr. Hirzy at 202-260-4683. His E-mail address is<hirzy;ohr.r ep.a.gon>
<br /> END NOTE LITERATURE CITATIONS
<br /> 1.Applying the NAEP code of ethics to the Environmental Protection Agency and the fluoride in drinking water standard. Carton, R.J.
<br /> and Hirzy, J.W. Proceedings of the 23rd Ann. Conf. of the National Association of Environmental Professionals. 20-24 June, 1998.
<br /> GEN 51-61. On-line at rttpl/ net/--fuoride naep htm
<br /> 2. Neurotoxicity of sodium fluoride in rats. Mullenix, P.J., Denbesten, P.K., Schunior,A. and Keman,W.J. Neurotoxicol. Teratol. 17
<br /> 169-177(1995)
<br /> 3. Influence of chronic fluorosis on membrane lipids in rat brain.Z.Z. Guan,Y.N. Wang, K.Q.Xiao, D.Y. Dai,Y.H.Chen, J.L. Liu, P.
<br /> Sindelar and G. Dallner, Neurotoxicology and Teratology 20 537-542(1998).
<br /> 4.Chronic administration of aluminum-fluoride or sodium-fluoride to rats in drinking water: alterations in neuronal and
<br /> cerebrovascular integrity. Varner, J.A., Jensen, K.F., Horvath, W.And Isaacson, R.L. Brain Research 784 284-298(1998).
<br /> 5.Effect of high fluoride water supply on children?s intelligence. Zhao, L.B., Liang, G.H., Zhang, D.N., and Wu, X.R. Fluoride 29 190-
<br /> 192 (1996)
<br /> 6.Effect of fluoride exposure on intelligence in children. Li,X.S.,Zhi,J.L., and Gao, R.O. Fluoride 28 (1995).
<br /> 7.Effect of fluoride on the physiology of the pineal gland. Luke, J.A. Caries Research 28 204(1994).
<br /> 8.Newburgh-Kingston caries-fluorine study XIII. Pediatric findings after ten years. Schlesinger, E.R., Overton, D.E., Chase, H.C.,and
<br /> Cantwell, K.T. JADA 52 296-306(1956).
<br /> 9.Memorandum dated May 1, 1990. Subject: Fluoride Conference to Review the NTP Draft Fluoride Report; From:Wm. L. Marcus,
<br /> Senior Science Advisor ODW;To:Alan B. Hais,Acting Director Criteria&Standards Division ODW.
<br /> 10.Toxicology and carcinogenesis studies of sodium fluoride in F344/N rats and B6C3F1 mice. NTP Report No. 393(1991).
<br /> 11a. Chromosome aberrations, sister chromatid exchanges, unscheduled DNA synthesis and morphological neoplastic
<br /> transformation in Syrian hamster embryo cells.Tsutsui et al. Cancer Research 44 938-941 (1984).
<br /> 11b. Cytotoxicity, chromosome aberrations and unscheduled DNA synthesis in cultured human diploid fibroblasts. Tsutsui et al.
<br /> Mutation Research 139 193-198(1984).
<br /> 11c. Positive mouse lymphoma assay with and without S-9 activation; positive sister chromatid exchange in Chinese hamster ovary
<br /> cells with and without S-9 activation; positive chromosome aberration without S-9 activation. Toxicology and carcinogenesis studies
<br /> of sodium fluoride in F344/N rats and B6C3F1 mice. NTP Report No. 393 (1991).
<br /> 11d.An increase in the number of Down's syndrome babies born to younger mothers in cities following fluoridation. Science and
<br /> Public Policy 12 36-46(1985).
<br /> 12.A brief report on the association of drinking water fluoridation and the incidence of osteosarcoma among young males. Cohn,
<br /> P.D. New Jersey Department of Health (1992).
<br /> 13.Surveillance, epidemiology and end results(SEER)program. National Cancer Institute in Review of fluoride benefits and risks.
<br /> Department of Health and Human Services. F1-F7 (1991).
<br /> 14.New evidence on fluoridation. Diesendorf, M., Colquhoun, J., Spittle, B.J., Everingham, D.N., and Clutterbuck, F.W. Australian
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