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Cannabis and Cannabinoid Research <br /> Volume 2.1,2017 Cannabis and <br /> DOI: 10.1089/can.2017.0012 Cannabinoid Research <br /> M 1.,..zkC114, (4,G.A 4444414 <br /> ORIGINAL RESEARCH Open Access <br /> Cannabis as a Substitute for Opioid-Based Pain Medication: <br /> Patient Self-Report <br /> Amanda Reiman,'* Mark Welty,2 and Perry Solomon3 <br /> Abstract <br /> Introduction: Prescription drug overdoses are the leading cause of accidental death in the United States.Alter- <br /> natives to opioids for the treatment of pain are necessary to address this issue.Cannabis can be an effective treat- <br /> ment for pain,greatly reduces the chance of dependence,and eliminates the risk of fatal overdose compared to <br /> opioid-based medications. Medical cannabis patients report that cannabis is just as effective, if not more,than <br /> opioid-based medications for pain. <br /> Materials and Methods:The current study examined the use of cannabis as a substitute for opioid-based pain <br /> medication by collecting survey data from 2897 medical cannabis patients. <br /> Discussion: Thirty-four percent of the sample reported using opioid-based pain medication in the past 6 <br /> months. Respondents overwhelmingly reported that cannabis provided relief on par with their other medica- <br /> tions, but without the unwanted side effects. Ninety-seven percent of the sample "strongly agreed/agreed" <br /> that they are able to decrease the amount of opiates they consume when they also use cannabis, and 81% <br /> "strongly agreed/agreed"that taking cannabis by itself was more effective at treating their condition than taking <br /> cannabis with opioids. Results were similar for those using cannabis with nonopioid-based pain medications. <br /> Conclusion:Future research should track clinical outcomes where cannabis is offered as a viable substitute for pain <br /> treatment and examine the outcomes of using cannabis as a medication assisted treatment for opioid dependence. <br /> Keywords:opiates; pain; harm reduction;substitution;opioids;cannabis <br /> Introduction 1999."1 Interestingly, Bachhuber et al. found that states <br /> The Centers for Disease Control (CDC) and Preven- with medical cannabis laws had significantly lower state- <br /> tion report that "[o]pioids (including prescription level opioid overdose mortality rates.2 Similarly,Bradford <br /> opioid pain relievers and heroin) killed more than and Bradford evaluated data on all prescriptions filled by <br /> 28,000 people in 2014,more than any year on record." Medicare Part D patients from 2010 to 2013 and found <br /> Unfortunately,this statistic has done little to curb the that the use of prescription drugs for which cannabis <br /> prescribing and consumption patterns for prescription could serve as a clinical alternative fell significantly, once <br /> opioids.The CDC estimates that,"since 1999,the amount a state medical cannabis law was implemented. They <br /> of prescription opioids sold in the United States nearly found that implementing an effective medical cannabis <br /> quadrupled, yet there has not been an overall change in law led to a reduction of 1826 daily doses for opioid <br /> the amount of pain that Americans report. Deaths from pain relief filled per physician per year.3 <br /> prescription opioids—drugs like oxycodone, hydroco- Patients who suffer with pain continue to use opioids <br /> done, and methadone—have also quadrupled since for chronic pain conditions despite their limited long- <br /> 'School of Social Welfare,University of California,Berkeley,Berkeley,California. <br /> 'School of Lifespan Development and Educational Services,Kent State University,Kent,Ohio. <br /> 3Chief Medical Officer,HelloMD,San Francisco,California. <br /> *Address correspondence to:Amanda Reiman,PhD,MSW,School of Social Welfare,University of California,Berkeley, 120 Haviland Hall,Berkeley,CA 94720,E-mail: <br /> areiman@berkeley.edu <br /> ©Amanda Reiman et al.2017;Published by Mary Ann Liebert,Inc.This is an Open Access article distributed under the terms of the Creative Commons <br /> Attribution License,which permits unrestricted use,distribution,and reproduction in any medium,provided the original work is properly cited. <br /> 160 <br /> /h <br />