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Reiman,et al.;Cannabis and Cannabinoid Research 2017,2.1 165 <br /> http://online.liebertpub.com/doi/10.1089/can.2017.0012 <br /> 63% 56° < .. 68% <br /> 67% <br /> . _.._ ._.._ .r.Cs.��,:�;.�°'r.`.• �.�. �rb°.:a+.,. '�.,.: _-..13,.E ..u:i..... -- 'r J.x ,. <br /> Cannabis works Need less Cannabis is Prefer cannabis Would use more <br /> well with my NOPM when more effective to NOPM as a substitute <br /> NOPM using cannabis than NOPM it available <br /> ■ Strongly Disagree Disagree ■ Agree ■ Strongly Agree <br /> FIG. 3. Use of cannabis as a substitute/in conjunction with nonopioid based medication (n=1684). <br /> results of this study support that not only is this prac- cannabis use for pain. This may have biased the respon- <br /> tice common but also medical cannabis patients who dents toward those using for pain versus other conditions. <br /> choose to use cannabis as a substitute for these med- <br /> icines report better outcomes with fewer unwanted Response rate <br /> side effects with cannabis compared to their other The survey yielded responses from 2897 participants, <br /> medications. which is a response rate of 4.3%. Since the survey <br /> Participants in this study overwhelmingly supported was sent to the HelloMD total patient database,includ- <br /> the notion that they would be more likely to use cannabis ing those not using cannabis for pain,this could reflect <br /> as a substitute for pain medication if it were less stigma- in the response rate. Other reasons for nonresponse, <br /> tized and more available, suggesting that there are pop- besides lack of interest,include people who are no lon- <br /> ulations of people who could benefit from this practice ger patients and those who chose not to participate for <br /> but are shying away due to the stigma and legal restric- other reasons such as privacy concerns. <br /> tions related to cannabis use.If cannabis laws continue to <br /> change across the country,it will be important to assess Amount of cannabis consumed <br /> how changes in these laws might impact other public One of the major limitations of cannabis research is the <br /> health behaviors and outcomes,such as opioid overdose, difficulty in determining how much cannabis partici- <br /> dependence, risky behaviors, and spending on prescrip- pants are using. Variations in strength of product, <br /> tion medications. size of vessel, and social use patterns all impact the re- <br /> liability and validity of consumption measures. This <br /> Limitations survey did not ask participants to estimate their amount <br /> This is a study of patient self-report through online survey. of consumption and therefore cannot comment on <br /> The data for analyses are based on patient perception and reported effective doses. <br /> not on objective measure of cannabis and opioid use.Fur- <br /> thermore, there is no comparison group of pain patients Prescription status of opioids <br /> who only have access to opioid-based medications or in- This study did not ask participants if the opioids they con- <br /> dividuals solely using over-the-counter medications for sumed were from a prescription or by self-medication. <br /> pain. Finally,the solicitation e-mail sent to potential par- The study also did not inquire as to the specific types <br /> ticipants included the title of the study which relates to of opioids being consumed. <br />